ImmunoEngineering is an emerging area and involves the application of engineering tools and principles to quantitatively study the immune system in health and diseases and to develop therapeutic interventions for precisely controlling and modulating a patient’s immune response. ImmunoEngineering research in BME interfaces with the Center for ImmunoEngineering at Georgia Tech as well as partner centers at Emory University and deals with a broad range of scientific problems including; Biophysical understanding of molecular and cellular interactions of the immune system. Systems immunology including quantitative and high throughput assessment of the immune status and mathematical modeling of immune interactions. Immunomodulatory therapies using cellular, molecular and biomaterial-based approaches for vaccine development against infectious diseases and cancer, control of the immunological-environment in regenerative medicine, amelioration of autoimmune disorders and control of the innate immune, inflammatory, and wound healing response. Thus, we aim to contribute immunological knowledge, with the ultimate goal of developing breakthrough engineering tools and methods for personalized and predictive health care in patients.