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Gang Bao
Gang Bao
Professor, Rice University’s Department of Bioengineering
BioScience Research Collaborative
713.348.2764
Research Interests:

Biomolecular engineering, bionanotechnology, molecular imaging, molecular biomechanics

Research in the Bao lab is centered at developing nanotechnologies and biomolecular engineering approaches for basic biological studies and medicine, which spans the spectrum from chemical synthesis to small animal studies. Current methodology development includes the superparamagnetic nanoparticle probes, quantum dot bioconjugates, activitable molecular probes and molecular beacons for cellular and in vivo imaging, with applications in disease detection and mechanistic studies. The Bao lab also develops novel strategies for drug/gene delivery using targeted nanoparticles, gene targeting approaches for treating single-gene disorders and other diseases using engineered nucleases, as well as bioinformatics tools and engineered nanodevices driven by biomolecular motors. The development of the methodologies involves nanoprobe and nanodevice design and validation, synthesis of biomolecules and nanoparticles, bioconjugation, specific tagging and targeting, cellular delivery, surface modification, protein production and purification, as well as addressing issues such as sensitivity, specificity, spatial and temporal resolution and signal-to-background ratio in molecular imaging, and efficacy in disease treatment. These novel technologies and methods have a broad range of applications, both in basic biological research, and disease studies.

Publications:
  

Map of Coulter Department of Biomedical Engineering at Georgia Tech and Emory University

BME @ Emory

Coulter Department of Biomedical Engineering
Georgia Institute of Technology &
Emory University School of Medicine

BME @ GT:
313 Ferst Drive, Room 2127 Atlanta, GA 30332
Phone: 404.385.0124 :: Fax: 404.894.4243

TEP @ GT:
387 Technology Circle NW Atlanta, GA 30313
Phone: 404.385.0124 :: Fax: 404.894.4243

BME @ Emory:
1760 Haygood Dr, Ste W 200 Atlanta, GA
30322-4250
Phone: 404.727.9874 :: Fax: 404.727.9873