"Biomedical Micro- and Nanofluidics"
Shuichi Takayama, Ph.D.
Wallace H. Coulter Department of Biomedical Engineering
We construct organs-on-a-chip systems to dissect cell signaling pathways, understand disease physiology, test therapeutics, and perform cell-based therapies. Tunable nanofluidic systems are used to perform multi-color histone mapping of single strands of chromatin. And aqueous two phase systems (ATPS) micropatterning enables cell printing and droplet-based bioassays.
Examples of specific projects include: Microfluidic models of cancer metastasis, Lung-on-a-chip, In vitro fertilization on a chip, Phase locking analysis in GPCR signaling, and Validation of protein biomarkers of disease for development of diagnostics.