Barbara D. Boyan, Ph.D.
Professor
Price Gilbert, Jr. Chair in Tissue Engineering
Associate Dean for Research, College of Engineering
Georgia Research Alliance Eminent Scholar

Wallace H. Coulter Dept. of Biomedical Engineering
Georgia Institute of Technology
Atlanta, GA 30332-0363

Phone:404-385-4108
Fax:404-894-2291
Location:GT: IBB - 1108
E-Mail: barbara.boyan@bme.gatech.edu
URL:

Areas of Research

• Mechanism of action of hormones and growth factors in chondrocytes and osteoblasts
• Normal and pathological calcification
• Tissue engineering
• Response of cells to biomaterials

Educational Background

• Ph.D. Rice University, 1975
• M.A. Rice University, 1974
• B.A. Rice University, 1970

Selected Awards

• Fellow, American Institute of Mechanical and Biological Engineering, 2006
• Atlanta Woman of the Year (Science), 2005
• The Birnberg Research Award, Columbia University School of Dental and Oral Surgery, 2003
• Fellow, American Association for the Advancement of Science, 2002
• Society for Biomaterials Clemson Award for Contributions to the Literature, 2001
• Albert-Hoffa-Prize (with Drs CH Lohmann, Z Schwartz, Y Liu, H Guerkov, B Simon, BD Boyan), Die Norddeutsche Orthop denvereinigung e.V (North German Orthopaedic Society) Research Prize, 2001
• American Academy of Periodontolgy, R. Earl Robinson Regeneration Award (with Drs Z Schwarts, DD Dean, CH Lohmann, D Andreacchio, TC Weesner, DL Carnes, DL Cochran), October, 2001

Selected Research Publications

• Wang L, Zhao G, Olivares-Navarrete R, Bell B, Wieland M, Cochran DL, Schwartz Z, Boyan BD. Integrin 1 silencing in osteoblasts alters substrate-dependent responses to 1,25-dihydroxy vitamin D3. Biomaterials 9(27): 3716-3725, 2006.
• Zhao G, Zinger O, Schwartz Z, Wieland M, Landolt D, Boyan BD. Osteoblast-like cells are sensitive to submicron-scale surface structure. Clinical Oral Implant Research 17(3): 258-64, 2006.
• Ranly DM, McMillan J, Krause WF, Lohmann CH, Boyan BD, Schwartz Z. Platelet-rich plasma in bone repair. Encyclopedia of Biomedical Engineering; Volume 5, John Wiley & Sons, Inc., Hoboken, NJ, Editor, Metin Akay, pp. 2804-2815, 2006.
• Boyan BD, Wang L, Wong K, Jo H, Schwartz Z. Plasma membrane requirements for 1a,25(OH)2D3 dependent PKC signaling in chondrocytes and osteoblasts. Steroids 71(4): 286-90, 2006. Epub 2005 Dec 1.
• Schwartz Z, Graham EJ, Wang L, Lossdorfer S, Gay I, Johnson-Pais TL, Carnes DL, Sylvia VL. Phospholipase A(2) activating protein (PLAA) is required for 1alpha,25(OH)(2)D(3) signaling in growth plate chondrocytes. J Cell Physiol 203(1): 54-70, 2005.
• Schwartz Z, Nasatzky E, Boyan BD. Surface microtopography regulates osteointegration: the role of implant surface microtopography in osteointegration. Alpha Omegan 98(2): 9-19, 2005.
• Ranly DM, McMillan J, Keller T, Lohmann CH, Meunch T, Cochran DL, Schwartz Z, Boyan BD. Platelet-derived growth factor inhibits demineralized bone matrix-induced intramuscular cartilage and bone formation. A study of immunocompromised mice. J Bone Joint Surgery 87(9): 2052-2064, 2005.
• Nemere I, Farach-Carson MC, Rohe B, Sterling TM, Norman AW, Boyan BD, Safford SE. Ribozyme knockdown functionally links a 1,25(OH)2D3 membrane binding protein (1,25D3-MARRS) and phosphate uptake in intestinal cells. Proc Natl Acad Sci USA 101(19): 7392-7, Epub 2004 Apr 29.