|
Areas of Research
Gene therapy, Engineering of gene transfer technologies, Retrovirus-cell interactions, Applications of gene therapy to cellular and tissue engineering.
Educational Background
- Postdoctoral Fellow, Harvard Medical School and the Shriners Burns Institute, 1998-1999
- Ph.D. Rutgers University, 1998
- M.S. Cornell University, 1987
- B.S. Cornell University, 1986
Selected Awards
- 2005, Educational Partnership Award
- 2002 - 2007, CAREER Award, National Science Foundation
Selected Research Publications
- Phillips, J.E., Burns, K.L., Le Doux, J.M., Guldberg, R.E., and Garcia, A.J. "Engineering Graded Tissue Interfaces", PNAS (2008)
- Chilton, J.M. and Le Doux, J.M. "Complexation of retroviruses with polymers significantly increases the number of genes transferred to murine embryonic stem cells but does not raise transgene expression levels", Biotechnology and Applied Biochemistry, 2008
- Landazuri, N. and Le Doux, J.M. "Amphotropic Retrovirus Transduction is Inhibited by High Doses of Particle-associated Envelope Proteins", Biotechnology and Bioengineering, 99(5):1205-1215 (2008)
- Jung, C., and Le Doux, J.M. "Lentiviruses Inefficiently Incorporate Human Parainfluenza Virus Type 3 Envelope Proteins", Biotechnology and Bioengineering, 99(4):1016-1027 (2008)
- Krishna, D., and Le Doux, J.M. "Murine Leukemia Virus Particles Activate Rac1 in HeLa Cells", Biochemical and Biophysical Research Communications, 345(3):1184-1193 (2006)
- McMillin, D.W., Landazuri, N., Gangadharan, B., Hewes, B., Archer, D., Spencer, H.T., and Le Doux, J.M. "Highly efficient transduction of repopulating bone marrow cells using rapidly concentrated polymer-complexed retrovirus", Biochemical and Biophysical Research Communications, 330:768-775 (2005)
|
