News

Gautam Goel graduated and moved on to Harvard. Congratulations!



Voit Lab part of a $6 Million NIEHS sponsored project addressing Parkinson's disease.



Voit Lab part of a $125 Million Department of Energy sponsored project for improvements in biofuel production.



Since January 1, 2008, Voit leads Georgia Tech's new Integrative BioSystems Institute as its first director. Click here for further information.






Recent Papers:

Chou, I-C. and E.O. Voit: Recent Developments in Parameter Estimation and Structure Identification of Biochemical and Genomic Systems. Math. Biosc. 219, 57-83, 2009.

Voit, E.O.: Foreword. Int. J. Syst. Synth. Biol. in press, 2009.

Voit, E.O. and I-C. Chou: Parameter Estimation in Canonical Biological Systems Models. Int. J. Syst. Synth. Biol. in press, 2009.

Vilela, M., S. Vinga, M. A. Grivet Mattoso Maia, E. O. Voit, J. S. Almeida: Identification of neutral sets of biochemical systems models from time series data. BMC Systems Biology 3:47, 2009.

Qi, Z., G. W. Miller, and E. O. Voit: Computational analysis of determinants of dopamine dysfunction. Synapse 63, 1133-1142, 2009.

Ko, C.-L., E.O. Voit, and F.-S. Wang: Estimating Parameters for Generalized Mass Action Models with Connectivity Information. BMC Bioinformatics. in press, 2009.

Voit, E.O., G. Goel , I-C. Chou, and L. da Fonseca: Estimation of Metabolic Pathway Systems from Different Data Sources. IET Systems Biol. in press, 2009.

Wu, J. and E.O. Voit: Integrative Biological Systems Modeling: Challenges and Opportunities. Frontiers of Computer Science in China. 3(1), 92-100, 2009.

Wu, J. and E.O. Voit: Hybrid Modeling In Biochemical Systems Theory by Means of Functional Petri nets Journal of Bioinformatics and Computational Biology. J. Bioinf. Comp. Biol. 7(1), 107-134, 2009.

Voit, E.O.: A Systems-Theoretical Framework for Health and Disease. Abstract modeling of inflammation and preconditioning. Math. Biosc. 217, 11-18, 2009.

Vodovotz, Y., G. Constantine, J. Rubin, M. Csete, E.O. Voit, and G. An: Mechanistic Simulations of Inflammation: Current State and Future Prospects. Math. Biosc. 217, 1-10, 2009.

Voit, E.O., F. Alvarez-Vasquez, and Y.A. Hannun: Computational Analysis of Sphingolipid Pathway Systems. In: C. Chalfant and M. Del Poeta: Sphingolipids as Signaling and Regulatory Molecules, Landes Bioscience, Austin, TX, in press

Voit, E.O. and M. L. Kemp: Systems biology graduate training in engineering schools. Proc. of Foundations of Systems Biology in Engineering (FOSBE) 2009, in press

Voit, E.O.: Mathematical Modeling as a Tool for Decoding the Control of Metabolic Pathways. Chapter 9 in: P. N. Lithaw (Ed.) Glycolysis: Regulation, Processes and Diseases. Nova Science Publishers, Inc., Hauppauge, NY 2009.

Goel, G., I-C. Chou, and E.O. Voit: System Estimation from Metabolic Time Series Data. Bioinformatics 24, 2505-2511, 2008.

Voit, E.O. and S.R. Veflingstad: Systems Biology as an Inspiration for Mechatronics. J. Biomechatronics Engng. 1(1), 55-69, 2008.

Weitz, J.S., Y. Mileyko, R.I. Joh, and E.O. Voit: Collective decision making in bacterial viruses. Biophys. J. 95(6), 2673-2680, 2008. (highlighted in Nature)

Yin, W. and E. O. Voit: Construction and Customization of Stable Oscillation Models in Biology. J. Biol. Systems 16(4), 463-478, 2008.

Qi, Z., G. W. Miller, and E. O. Voit: A Mathematical Model of Presynaptic Dopamine Homeostasis: Implications for Schizophrenia. Pharmacopsychiatry 41(Suppl. 1): S89-S98, 2008.

Voit. E.O., Z. Qi, and G.W. Miller: Modeling Complex Biological Systems, One Step at a Time. Pharmacopsychiatry 41(Suppl. 1): S78-S84, 2008.

Qi, Z., G. W. Miller, and E. O. Voit: Computational systems analysis of dopamine metabolism. PLoS One 3(6):e2444, 2008.

Garcia, J., J. Shea, F. Alvarez-Vasquez, A. Qureshi, C. Luberto, E. O. Voit, and M. Del Poeta: Mathematical modeling of pathogenicity of Cryptococcus neoformans. Molecular Systems Biology. 4:183, 2008.

Vilela, M., I-C.Chou, S. Vinga, A.T.R Vasconcelos, E.O. Voit, and J.S. Almeida: Parameter optimization in S-system models. BMC Systems Biol. 16; 2:35, 2008.

Voit, E. O. and K. L. Brigham: The role of systems biology in predictive health and personalized medicine. The Open Path. J. 2, 68-70, 2008.

Feinendegen, L., P. Hahnfeldt, E.E. Schadt, M. Stumpf, and E.O. Voit: Systems Biology and its Potential Role in Radiobiology. Radiation and Environmental Biophysics 47(1), 5-23, 2008.

del Rosario, R.C.H., E. Mendoza, and E.O. Voit: Challenges in lin-log modeling of glycolysis in Lactococcus lactis. IET Systems Biol. 2(3), 136-149, 2008.

Alvarez-Vasquez, F., Y. A. Hannun, and E. O. Voit. Dynamics of positional enrichment: Theoretical development and application to carbon labeling in Zymomonas mobilis. Biochem. Eng. J. 40(1), 157-174, 2008.

Garcia, S.P, E. L. Krug, J. M. Arthur, E. O. Voit, R. Stanislaus, and J. S. Almeida. Follow the leader: deciphering biological systems from dynamical networks. BMC Bioinformatics 7; 9:4, 2008.

Polisetty, P.K., E.O. Voit, and E. P. Gatzke: Yield Optimization of Regulated Metabolic Systems Using Deterministic Methods. Biotech. Bioengin. 99(5), 1154-1169, 2008.

Voit, E.O.: Canonical Modeling. In: Encyclopedia for Quantitative Risk Assessment. Wiley and Sons (expected 2008).

Mao, F., H. Wu, P. Dam, I-C. Chou, E. O. Voit, and Y. Xu: Prediction of Biological Pathways through Data Mining and Information Fusion. In: Y. Xu and J.P. Gogarten (Eds.) Computational Methods for Understanding Bacterial and Archaeal Genomes, Imperial College Press, London, U.K., pp. 281-314, 2008.

Veflingstad, S., P. Dam, Y. Xu, and E. O. Voit: Microbial Pathway Models. In: Y. Xu and J.P. Gogarten (Eds.) Computational Methods for Understanding Bacterial and Archaeal Genomes, Imperial College Press, London, U.K., pp. 315-344, 2008.

Voit, E.O.: Modeling Networks using Power-Laws and S-Systems. In: O. Wolkenhauer (Ed.) Systems Biology, Essays in Biochemistry Series, Vol. 45, Portland Press, pp. 29-40, 2008.

Voit, E.O.: Model Identification: A Key Challenge is Computational Systems Biology. in: Optimization and Systems Biology; Lecture Notes in Operations research, Vol. 9; Series Editors: D.-Z. Du and X.-S. Shang. World Publishing Corp., pp. 1-12, 2008.