People

Dongin (Donoven) Kim, Ph.D.
Post Doctoral Fellow

Short Biography

RESEARCH PROJECT

Small molecular cancer imaging and therapy

EDUCATION/BACKGROUND      

Mar. 2009 – Present, Georgia Institute of Technology, Atlanta, GA
        Post-doc fellow
        Project: Small molecular cancer imaging and therapy

Aug. 2003 – Feb. 2009  University of Utah, Salt Lake City, UT
        PhD in Pharmaceutics and Pharmaceutical Chemistry
        Project: A pH sensitive polymeric micelle targeting multidrug resistant (MDR) tumor
        
Aug.2000 – Dec.2002  University of Florida, Gainesville, FL
        M. S. in Material Science and Engineering
        Project: Interaction of Nanoparticle with Blood Constituents
        
Mar.1992 – Feb.1999  Ajou University, Suwon, Korea (South)
        B. S. in Applied Chemistry

PUBLICATIONS

D. Kim, Z.G. Gao, E.S. Lee, Y.H. Bae 2009 In vivo evaluation of doxorubicin-loaded polymeric micelles targeting folate receptors and early endosomal pH in drug-resistant ovarian cancer, Mol. Pharmaceutics (under review)

Z. Gao, D. Kim, E.S. Lee, Y.H. Bae 2008 Visualization of pH-sensitive nanoparticle extravasation from breast cancer tumor microvessel in window chamber model, Microvascular research (submitted)

D. Kim, E.S. Lee, K.T. Oh, Z.G. Gao, Y.H. Bae 2008 Doxorubicin-loaded polymeric micelle overcomes multidrug resistance of cancer by double-targeting folate receptor and early endosomal pH, Small 4 (11):2043-2050

D. Kim, E.S. Lee, K. Park, I.C. Kwon, Y.H. Bae 2008 Doxorubicin loaded pH-sensitive micelle: antitumoral efficacy against ovarian A2780/DOXR tumor and optical imaging of epidermoid KB tumor, Pharm. Res. 25 (9):2074-208

B.S. Jin, H.C. Kang, D. Kim, K.H. Lee, Y.H. Bae 2008 Synthesis of poly(cystine bisamide)-PEG block copolymers grafted with 1-(3-aminopropyl) imidazole and their phase transition behaviors, Polym. Adv. Technol. 19:1558-1565

E.S. Lee, Z.G. Gao, D. Kim, K. Park, I.C. Kwon, Y.H. Bae 2008 Super pH-sensitive multifunctional polymeric micelle for tumor pHe specific TAT exposure and multidrug resistance, J. Control. Release 129: 228-236

E.S. Lee, D. Kim, Y. S. Youn, K.T. Oh, Y.H. Bae 2008 A Novel Virus-Mimetic Nanogel Vehicle, Angew. Chem. Int. Ed. 47(13):2418-2421 (Highlighted in Nature Nanotechnology 7 March 2008 | doi:10.1038/nnano.2008.70)

K.T. Oh, E.S. Lee, D. Kim, Y.H. Bae 2008 L-Histidine based pH-sensitive anticancer drug carrier micelle: Reconstitution and brief evaluation of its systemic toxicity, Int. J. Pharm. 358: 177–183

H. Yin, E.S. Lee, D. Kim, K.H. Lee, K.T. Oh, Y.H. Bae 2008 Physicochemical Characteristics of pH-sensitive Poly(L-Histidine)-b-Poly(ethylene glycol)/Poly(L-lactic acid)-b-poly(ethylene glycol) mixed micelles, J. Control. Release 126:130–138

E.S. Lee, K.T. Oh, D. Kim, Y.S. Youn, Y.H. Bae 2007 Tumor pH-responsive flower-like micelles of poly(L-lactic acid)-b-poly(ethylene glycol)-b-poly(L-hisitidine), J. Control. Release 123:19-26

Z.G. Gao, D.H. Lee, D. Kim, Y.H. Bae 2005 Doxorubicin loaded pH-sensitive micelle targeting acidic extracellular pH of human ovarian A2780 tumor in mice, J. Drug Targeting 13(7): 391-397

D. Kim, H. El-Shall, D. Dennis, T. Morey 2005 Interaction of PLGA nanoparticles with human blood constituents, Colloids and Surfaces B: Biointerfaces 40: 83-91