People

Chen-Yu Kao
Ph.D. Student

Short Biography

RESEARCH PROJECT

Chen-Yu’s project is to develop high molecular weight polyketals for drug delivery applications. The overall goal of his project is to improve the delivery of calpain inhibitors to the spinal cord, for the treatment of amyotrophic lateral sclerosis (ALS), using polyketal microparticles. He is also interested to deliver different therapeutic agents (siRNAs, peptides and enzymes) to treat other acute or chronic inflammatory diseases (acute liver failure and arthritis) using polyketal microparticles which have different release rates.

EDUCATION/BACKGROUND

Jun. 2007 - Present

Georgia Institute of Technology, Biomedical Engineering Department

Ph.D. Candidate

Advisor: Niren Murthy

Jul. 2003 - Jun. 2007

Georgia Institute of Technology, Biomedical Engineering Department

Master of Science in Biomedical Engineering,

Advisor: Ravi Bellamkonda

Aug. 2001—Jun. 2003

Case Western Reserve University, Biomedical Engineering Department

Advisor: Ravi Bellamkonda

Sep. 1998 – Jun. 2000

National Chung Cheng University, Chia-yi, Taiwan

Master of Science in Chemical Engineering

Oct. 1989 – Jun.1993

Chung Yuan Christian University, Chung-Li, Taiwan

Bachelor of Science in Chemical Engineering

PUBLICATIONS

    Mukundan S Jr, Ghaghada KB, Badea CT, Kao CY, Hedlund LW, Provenzale JM, Johnson GA, Chen E, Bellamkonda RV,                     Annapragada A. (2006) A liposomal nanoscale contrast agent for preclinical CT in mice. AJR Am J Roentgenol. 186(2):300-7.

    Kao CY, Hoffman EA, Beck KC, Bellamkonda RV, Annapragada AV (2003). Long-residence-time nano-scale liposomal iohexol         for X-ray-based blood pool imaging. Acad Radiol. 10(5):475-83

    Kao CY, Lo TC, Lee WC, (2003) Influence of polyvinylpyrrolidone on the hydrophobic properties of partially porous                         poly(styrene-divinylbenzene) particles for biological applications. J. Appl. Polym. Sci., Vol: 87, pp 1818 –24

    Huang FC, Ke CH, Kao CY and Lee WC (2001). Preparation and application of partially porous poly(styrene-divinylbenzene)         particles for lipase immobilization, J. Appl. Polym. Sci Vol 80, pp 39-46.

    Hsiue GH, Lee SD , Chang PC , Kao CY (1998), Surface characterization and biological properties study of silicone rubber             membrane grafted with phospholipid as biomaterial via plasma induced graft copolymerization, JBMR 42 (1):134 – 47

    Lee SD; Hsiue GH; Kao CY (1996) Preparation and characterization of a homobifunctional silicone rubber membrane grafted         with acrylic acid via plasma-induced graft copolymerization, Journal of Polymer Science, Part A: Polymer Chemistry. 34(1):             141-148.

    Lee SD, Hsiue GH, Chang PC, Kao CY (1996)Plasma-induced grafted polymerization of acrylic acid and subsequent grafting of     collagen onto polymer film as biomaterials. Biomaterials, 17(16):1599-608.

    Lee SD, Hsiue GH, Kao CY, Chang PC (1996) Artificial cornea: surface modification of silicone rubber membrane by graft                 polymerization of pHEMA via glow discharge. Biomaterials, 17(6):587-95.

HONORS