Jay C. Sy
Biomedical Engineering Ph.D. Student
PROJECT
Jay is currently collaborating with Dr. Niren Murthy on using novel polymer chemistries to treat myocardial infarcts. This project focuses on reducing oxidative stress and recovery of heart function following ischemia. Current approaches include delivering agents to block the p38 pathway, using siRNA to knockdown gene expression, and delivering agents to eliminate superoxide.
EDUCATION/BACKGROUND
Jay Sy earned his bachelors in science and engineering from the University of Pennsylvania in 2005. He majored in bioengineering with a minor in materials science and engineering. Following graduation, Jay worked as a research scientist at Vanderbilt University as a research scientist before joining the Biomedical Engineering joint program at Georgia Tech/Emory with a Department of Homeland Security Graduate Fellowship.
PATENTS
US Patent Application 60/556,637 (filed March 25, 2004) "Emulsion-based control of electrospun fiber morphology." VP Shastri, JC Sy, I-W Chen.
US Patent Application 60/619,156 (filed October 15, 2004) "Nano- and micro-scale engineering of polymeric scaffolds for vascular tissue engineering." VP Shastri, JC Sy.
US Patent Application 60/829,458 (filed October 13, 2006) "Modulation of drug release from electrospun fibers." VP Shastri, JC Sy, AS Klemm.
PUBLICATIONS
"Emulsion as a means of controlling electrospinning of polymers." JC Sy, VP Shastri.
"Towards Development of Surface Eroding Poly(-Hydroxy acids)." X-J Xu, JC Sy, VP Shastri. Biomaterials (May 2006, 27 (15): 3021-3030)
ABSTRACTS AND PRESENTATIONS
"Release of bioactive agents from nanofibers meshes electrospun from emulsions." JC Sy, AS Klemm, VP Shastri. 2006 Biomedical Engineering Society Fall Meeting
"Nano- and micro-scale engineering of synthetic vascular grafts." JC Sy and VP Shastri. 2004 Biomedical Engineering Society Fall Meeting
"Degradation behavior of novel poly(-hydroxy acid)-derived polyesters." JC Sy, X-J Xu, MM Stevens, and VP Shastri. 2004 Materials Research Society Spring Meeting
"Emulsion-based control of electrospun fiber morphology." JC Sy, I-W Chen, VP Shastri. 227th American Chemical Society National Meeting 2004
"Surface eroding polyesters derived from poly(-hydroxy acids)." X-J Xu, JC Sy, MM Stevens, VP Shastri
