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Welcome to the Biomedical Dynamics Modeling Lab, headed by Dr. Paul Benkeser. Take a look at our recent projects.
Recent ProjectsDynamic Modeling of the Right Ventricle In marked contrast to adult cardiology, which deals almost exclusively with the left ventricle, the function of the right ventricle is associated with a number of life threatening congenital defects in children. By utilizing MR data and catheter pressure measurements, a computer model that simulates both the heart wall and blood pool of the right ventricle is being developed. Wall parameters such as strain and thickening as well as blood parameters such as ejection fraction and pressure will be determined.
Velocity-aided Cardiac Segmentation and Physically-Based Cardiac Motion Tracking The accuracy of diagnosis of heart disease depends heavily on cardiac segmentation and motion tracking techniques. A new segmentation technique that is based on an active contour model and phase contrast MRI is used to extract the myocardial boundaries. Cardiac motion tracking is achieved utilizing phase contrast MRI to obtaining data correspondence over the entire cardiac cycle, and a new energy minimization scheme using elastic deformation potential energy is used to effectively reconstruct the through-plane motion of the heart.
Analysis of eye movement in patients with low vision is important to clinicians. Tracking horizontal, vertical, and rotational eyeball motion is achieved utilizing correlation algorithms from images obtained from a scanning laser ophthalmoscope.
Atherosclerosis is the leading cause of mortality and morbidity in industrialized countries. Progression of atherosclerotic disease is currently measured by determining vessel stenosis from ultrasound or X-ray imaging. Mechanical propeties of peripheral vessels are determined by an extension of the generalized motion model method.
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