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Areas of Research
Tissue remodeling in regenerative medicine; Microenvironmental cues modulating stem cell signaling networks
Educational Background
- Postdoctoral Fellow, Massachusetts Institute of Technology, 2006-2008
- Ph.D. Georgia Institute of Technology and Emory University, 2006
- B.S. Morehouse College, 2001
Selected Awards
- 2009, Georgia Cancer Coalition Distinguished Cancer Scholar
- 2008, FACES Career Initiation Grant
- 2007, UNCF/Merck Postdoctoral Science Research Fellowship
- 2006, FACES Portable Postdoctoral Fellowship
- 2003, NASA Harriett G. Jenkins Predoctoral Fellowship
- 2001, David and Lucile Packard Foundation Fellowship
Selected Research Publications
- Platt MO, Ankeny RF, Shi GP, Weiss D, Vega JD, Taylor WR, Jo H. “Expression of cathepsin K is regulated by shear stress in cultured endothelial cells and is increased in endothelium in human atherosclerosis.” Am J Physiol Heart Circ Physiol. 2007 Mar;292(3):H1479-86. Epub 2006 Nov 10.
- Platt MO, Xing Y, Jo H, Yoganathan AP. “Cyclic Pressure and Shear Stress inhibit Cathepsin activity and cathepsin L expression in porcine aortic valves.” J Heart Valve Dis. 2006 Sep;15(5):622-9.
- Platt MO, Ankeny RF, Jo H. “Laminar shear stress inhibits cathepsin L in endothelial cells.” Arterioscler Thromb Vasc Biol. 2006 Aug;26(8):1784-90.
- Pardo SJ, Patel MJ, Sykes MC, Platt MO, Boyd NL, Sorescu GP, Xu M, van Loon JJ, Wang MD, Jo H. “Simulated Microgravity Using the Random Positioning Machine Inhibits Differentiation and Alters Gene Expression Profiles of 2T3 Pre-osteoblasts.” Am J Physiol Cell Physiol. 2005 Feb 2.
- Sorescu GP, Song H, Tressel SL, Hwang J, Dikalov S, Smith DA, Boyd NL, Platt MO, Lassegue B, Griendling KK, Jo H. “Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress induces monocyte adhesion by stimulating reactive oxygen species production from a nox1-based NADPH oxidase.” Circ Res. 2004 Oct 15;95(8):773-9. Epub 2004 Sep 23.
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