Philip J. Santangelo, Ph.D.
Assistant Professor

Wallace H. Coulter Dept. of Biomedical Engineering
Georgia Institute of Technology and Emory University
Atlanta, GA 30332-0535

Phone: 404-385-2116
Fax: 404-894-4243
Location: GT: BME - 2107
E-Mail: philip.santangelo@bme.gatech.edu


Google Scholar: CLICK HERE

Areas of Research

infectious disease, molecular imaging, nano-biophotonics, and optical microscopy

Educational Background

• Ph.D., University of California, 1998
• M.S., Purdue University, 1994
• B.S., Polytechnic University, 1991

Selected Research Publications

• Jung, J, Lifland, AW, Zurla, C, Alonas, E, and Santangelo, PJ, Quantifying RNA-protein interactions in situ using modified-MTRIPs and proximity ligation, accepted for publication, Nucleic Acids Research, August 2012. Impact factor: 8.026
• Liu, Y, Ding, Y, Alonas, E, Zhao, W, Santangelo, PJ, Jin, D, Piper, JA, Teng, J, Ren, Q, and Xi, P, Achieving λ/10 Resolution CW STED Nanoscopy with a Ti:Sapphire Oscillator, PLoS ONE, 7(6), :e40003, 2012. Impact factor: 4.092
• Lifland, AW, Jung, J, Alonas, E, Zurla, C, Crowe, JE, Santangelo, PJ. Human respiratory syncytial virus nucleoprotein and inclusion bodies antagonize the innate immune response mediated by MDA5 and MAVS, Journal of Virology, 86(15): 8245-58, 2012. Impact factor: 5.402
• Shaikh, FY, Cox, RG, Lifland, AW, Hotard, AL, Williams, JV, Moore, ML, Santangelo, PJ, Crowe, JE, Jr. A critical phenylalanine residue in the respiratory syncytial virus fusion protein cytoplasmic tail mediates assembly of internal viral proteins into viral filaments and particles., mBio, 3(1), e00270-11, 2012. Impact factor: 5.311
• Santangelo, PJ, Alonas, E, Jung, J, Lifland, AW, and Zurla, C., Probes for Intracellular RNA Imaging In Live Cells, Methods in Enzymology, 505, 383-99, 2012. Impact factor: 2.042
• Zurla, C, Lifland, AW, and Santangelo, PJ, Characterizing mRNA interactions with RNA granules during translation initiation inhibition, PLoS ONE, 6(5), e19727, 2011. Impact factor: 4.092
• Lifland, AW, Zurla, C, Yu, J, and Santangelo, PJ, Dynamics of native β-actin mRNA transport in the cytoplasm, Traffic, 12, 1000-1011, 2011. Impact factor: 4.917
• Lindquist, M, Lifland, AW, Utley, TJ, Santangelo, PJ, and Crowe, JE, Jr., Respiratory syncytial virus induces host RNA stress granules to facilitate viral replication, Journal of Virology, 84(23), 12274-84, 2010. Impact factor: 5.402
• Lifland AW, Zurla C, and Santangelo PJ, Single Molecule Sensitive Multivalent Polyethylene Glycol Probes for RNA Imaging, Bioconjugate Chemistry, 21(3), 483-488, 2010. Impact factor: 4.930
• Santangelo, PJ, Molecular beacons and related probes for intracellular RNA imaging. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2(1), 11-19, 2010. Impact factor: 5.186
• Santangelo, PJ, Lifland, AW, Curt, P, Sasaki, Y, Bassell, GJ, Lindquist, M, and Crowe, JE, Jr., Single molecule-sensitive probes for imaging RNA in live cells, Nature Methods, 6 (5), 347-9, 2009. Impact factor: 19.276
• Utley TJ, Ducharme NA, Varthakavi V, Shepard B, Santangelo PJ, Lindquist ME, Goldenring JR, Crowe, JE, Jr., Respiratory syncytial virus uses a novel Vps4-independent budding mechanism controlled by Rab11-FIP2, Proc Natl Acad Sci., 105(29), 10209-14, 2008. Impact factor: 9.681